Vesicular stomatitis virus (VSV) is an enveloped non-segmented negative strand RNA virus belonging to the family Stomatoviridae. Its natural hosts are mainly horses, cattle and pigs. The viral genome consists of negatively polarized single-stranded RNA, and the 11,161-nt long genome contains five genes flanked by 3'-leading and 5'-tailing sequences. The genome sequence is 3'-leading-ribosomal protein (N)-phosphoprotein (P)-matrix protein (M)-glycoprotein (G)-large polymerase protein (L)-trailing-5'.
VSV usually plays an important role in promoting tumor lysis because of the defective innate immune response involving the interferon (IFN) system that may occur in tumor cells.
Structure of the VSV particles (Ge P et al., Science, 2010)
|
Customized product |
Content |
Period (working days) |
|
VSV (Indiana Strain) (total volume:2.00E+08 IFU) |
Molecular cloning (extra charge for gene synthesis) |
10 |
|
Virus Rescue |
10 |
|
|
Initial Identification |
3 |
|
|
Recombinant virus amplification, concentration |
5 |
|
|
Product quality inspection report (molecular identification) |
5 |
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US: 3675 Market Street, Suite 200, Philadelphia, PA19104 Tel: +1 (215) 205-6963 | +086 027-65023363
E-mail: hui.wang@genevoyager.com
China: No128, Guanggu 7th Rd, East Lake High-tech Development Zone, Wuhan, China Tel: 17720522078
E-mail: marketing@genevoyager.com
